Lsr2, a pleiotropic regulator at the core of the infectious strategy of Mycobacterium abscessus
ABSTRACTMycobacterium abscessus is a non-tuberculous mycobacterium, causing lung infections in cystic fibrosis patients.During pulmonary infection, M.abscessus switches from smooth (Mabs-S) to rough (Mabs-R) morphotypes, the latter being hyper-virulent.Previously, we isolated the lsr2 gene as differentially expressed during S-to-R transition.lsr2 e